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ColorDx Clinical Resources

ColorDx Clinical Resources

ColorDx Clinical Resources

ColorDx Clinical Resources

ColorDx Clinical Resources

ColorDx Clinical Resources

Growing Your Practice with Diagnostic Color Vision Testing

Operational Based Vision Assessment Cone Contrast Test: Description and Operation

Operational Based Vision Assessment Cone Contrast Test: Description and Operation

Gaska J, Winterbottom M, van Atta A. Operational Based Vision Assessment Cone Contrast Test: Description and Operation. USAF School of Aerospace Medicine, Aeromedical Research Department Wright-Patterson AFB; 2016 Jun 1.

A Performance Comparison of Color Vision Tests for Military Screening

A Performance Comparison of Color Vision Tests for Military Screening

Walsh DV, Robinson J, Jurek GM, Capó-Aponte JE, Riggs DW, Temme LA. A Performance Comparison of Color Vision Tests for Military Screening. Aerospace medicine and human performance. 2016 Apr 1;87(4):382-7.

Evaluation of Acquired Color Vision Deficiency in Glaucoma Using the Rabin Cone Contrast Test

Evaluation of Acquired Color Vision Deficiency in Glaucoma Using the Rabin Cone Contrast Test

Niwa Y, Muraki S, Naito F, Minamikawa T, Ohji M. Evaluation of Acquired Color Vision Deficiency in Glaucoma Using the Rabin Cone Contrast TestRabin Test for Glaucoma Color Vision Deficiency. Investigative ophthalmology & visual science. 2014 Oct 1;55(10):6686-90.

Evaluation of visual function impairments in patients with dry age-related macular degeneration

Evaluation of visual function impairments in patients with dry age-related macular degeneration

Lad EM, Chandramohan A, Ventura A, Cousins SW. Evaluation of visual function impairments in patients with dry age-related macular degeneration. Investigative Ophthalmology & Visual Science. 2014 Apr 30;55(13):5213-.

Rapid Quantification of Color Vision: The Cone Contrast Test

Rapid Quantification of Color Vision: The Cone Contrast Test

Rabin J, Gooch J, Ivan D. Rapid quantification of color vision: the cone contrast test. Investigative ophthalmology & visual science. 2011 Feb 1;52(2):816-20.

Rabin Color Cone Contrast Testing and Retinal Structure in Multiple Sclerosis

Rabin Color Cone Contrast Testing and Retinal Structure in Multiple Sclerosis

Samuel A, Yiu H, Songster C, Bolivar D, Gelfand J, Green A. Rabin Color Cone Contrast Testing and Retinal Structure in Multiple Sclerosis (P3. 227). Neurology. 2015 Apr 6;84(14 Supplement):P3-227.

Evaluation of clinical validity of the Rabin conecontrast test in normal phakic or pseudophakiceyes and severely dichromatic eyes

Evaluation of clinical validity of the Rabin conecontrast test in normal phakic or pseudophakiceyes and severely dichromatic eyes

Fujikawa M, Muraki S, Niwa Y, Ohji M. Evaluation of clinical validity of the Rabin cone contrast test in normal phakic or pseudophakic eyes and severely dichromatic eyes. Acta Ophthalmologica. 2017 May 31.

Visual function endpoints in early and intermediate dry age-related macular degeneration for use as clinical trial endpoints

Visual function endpoints in early and intermediate dry age-related macular degeneration for use as clinical trial endpoints

Cocce K, Stinnett S, Vajzovic L, Horne A, Toth CA, Cousins SW, Lad EM. Visual function endpoints in early and intermediate dry age-related macular degeneration for use as clinical trial endpoints. Investigative Ophthalmology & Visual Science. 2017 Jun 23;58(8):3765-.

Konan Medical ColorDx: Clinical Ocular Toxicology Substances and Pharmaceutical Agents that can Cause Color Vision Defects

Clinical Ocular Toxicology Substances and Pharmaceutical Agents that can Cause Color Vision Defects

Fraunfelder, Fraunfelder, Chambers. Clinical Ocular Toxicology. Sanders Elsevier, 2008: 320.

Konan Medical ColorDx: Assessment of Color Vision Screening Tests for U.S. Navy Special Duty Occupations

Assessment of Color Vision Screening Tests for U.S. Navy Special Duty Occupations

Reddix M, Williams H, Kirkendall C, Eggan S, Gao H, Wells W, O’Donnell O. AsMA 85th Scientific Meeting. May 2014.

Konan Medical's ColorDx: The US Army Color Vision Study

The US Army Color Vision Study

Capó-Aponte J, Temme L, Robinson J, Still D (May 2014). The US Army Color Vision Study. AsMA.

Konan Medical's ColorDx: Pilot Color Vision Research and Recommendations

Pilot Color Vision Research and Recommendations

Millrun N, Chidester T, Peterson S, Roberts C, Perry D, Gildea K. AsMA.  May 2013.

We have incorporated ColorDx at our practice over the past year with great results. We are able to get a much more detailed assessment of color vision status for our patients not only with congenital color vision deficits but more importantly for those with acquired color vision loss due to optic nerve disease and complications of high risk ocular medications such as Plaquenil. The system is easy to administer for our technicians and easy to perform for our patients.

The use of procedure code  92283 provides third party reimbursement that far more than offsets the cost of the system.  We highly recommend the ColorDx system for optometry and ophthalmology practices.

S. Barry Eiden, OD, FAAO

President and Medical Director, North Suburban Vision Consultants, Ltd.

The first patient I saw was a 3 year old whose mother complained she is having a hard time teaching her child colors and feels like the child is color blind.  Her child turned out to have a protan defect!  It was great because usually I would have to send someone to another office for extended color vision.  Glad I learned about this awesome product!
Alexia Vaughn, OD

Owner, Advanced Eye Care

normal protanProtan Factoids:

  • L-cone deficiency
  • Less discrimination of the red colors
  • Similar functionally to Deutans
  • Significantly more common in males (mutation on X-chromosome allele)
  • Commonly genetic cause, but may be acquired

A person with “red deficiency” or “red weakness” is a Protan and the condition is called Protanomaly. The appearance of “redness” by a color normal observer is seen more weakly by the Protan viewer both in terms of its color power (saturation or depth of color) and its brightness. Red, orange, yellow, and yellow-green appear somewhat shifted in “hue” (another word for color) towards green and appear less intense that they do to a color normal observer. The redness portion of a violet or lavender color is also weakened with a Protan so what appears contains mostly the blue component of the color. Thusly, what a color normal calls “violet, may appear only as another shade of blue to the Protan.

Under poor viewing conditions, such as when driving in dazzling sunlight or in rainy or foggy weather, Protan observers may mistake a blinking red traffic light for a blinking yellow, or fail to distinguish a green traffic light from the “white” lights in store fronts, street lights or other general lighting.

normal deutanDeutan Factoids:

  • M-cone deficiency
  • Less discrimination of the green colors
  • Similar functionally to Protans
  • Significantly more common in males (mutation on X-chromosome allele)
  • Commonly genetic cause, but may be acquired

A person with a Deutan deficiency called Deuteranomaly (5% of males) is considered to be “green weak” This deficiency is similar to the Protan type as there is also difficulty in discriminating between red – orange – yellow – green portions of the color spectrum … they are confused as being very similar. These colors seemed similar to the red portion of the spectrum.

Deuteranopia (1% of males) has the same hue discrimination problems as the Protonope, but without the dimming.

normal tritanTritan Factoids:
  • S-cone deficiency
  • Less discrimination of the blue colors
  • Typically an acquired condition (genetic basis is very rare)
  • May be the most common color deficiency type
  • No gender bias
  • Many tests that have been commonly administered in the past (Ishihara as an example) do not test for S-cone deficiencies
  • More common with age
    • Pharmaceutical agent toxicity may cause
    • Neurologic conditions, diseases and discorders may cause
    • Changes to the crystalline lens (cataracts) may cause

Sex-linked color blind traitRed-green color deficiencies are the most common type of genetic color vision deficiency, originating from an X-chromosome mutation which results in a color deficient allele.

This is a recessive trait, but females that are heterozygous (trait only on one X-chromosome) will not exhibit the inherited trait, rather it requires a homozygous condition where the trait is manifested on both chromosomes, i.e. inherited from both parents.

Males, that inherit trait on the single X-chromosome maternally, exhibit red-green color deficiency.

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