Endothelial cell morphology is like a ‘canary in the coal mine’…a potential warning that the structural stability of the endothelium has been affected, possibly by surgical procedures, disease, trauma or contact lenses.
CellChek Overview Video
Cataract Surgery and Premium IOLs
Low endothelial cell counts and pre-existing dystrophies can markedly reduce the potential for positive surgical outcomes from an otherwise uneventful cataract surgery. Surgeons are finding these data points critical when recommending premium IOLs: verify and document pre-operatively that the cornea is not suspect to more likely post-op complications difficult to explain with the investment in premium IOLs.
There are various reports in the literature of refractive surgery complications with corneas that have pre-existing dystrophies. It is incumbent on refractive surgeons and referring Optometrists to carefully assess the corneal health prior to performing or recommending an elective corneal surgery to enhance the potential for positive surgical outcomes.
General Corneal Health Assessment
Konan specular microscopy is an invaluable tool to screen for corneal diseases as such as Fuchs’ Dystrophy, keratoconus, other corneal dystrophies, and trauma. You won’t believe what you’ve been missing.
In the never ending battle to minimize the oxygen barrier from contact lens materials and lens hygiene, specular microscopy provides a highly detailed view of the integrity and distress of the cornea from the endothelium. As the “canary in the coal mine”, the endothelium can be an invaluable indicator of corneal distress.
It is not a coincidence ...
… that virtually every manufacturer of pharmaceutical agents and implantable devices that are required by the FDA to collect endothelial density as a primary safety endpoint, have had their clinical research teams, completely independently, assess the specular microscopes available on the market and have chosen Konan. Repeatedly.
Robust Analysis Methods
It all starts with robust data assessment of even the most difficult cases. Fully automated analysis is quick and easy, but Konan exclusively has options to maximize the sparse information on even advanced disease-state corneas.
FDA Cleared Database
Konan CellChek systems include robust database functions. Corneas with advanced disease states may be reanalyzed using more than one analysis strategy when there are few cells visualized and may be reassessed at a later date without overwriting original data.
Location ... Location ... Location
Easy location identification. Fixation direction is not enough – you cannot draw any conclusions about change over time unless you know the sample location.
Clear assessment of changes over time. Statistically valid trends can only be obtained if you are comparing same data locations.
Multi-point, optical, non-contact pachymetry allows comfortable assessment of corneal thickness without disruption of epithelium from probe contact or pharmaceutical agent
FDA Cleared Hardware and Software
Konan’s CellChek is EMR | EHR ready plus an optional DICOM interface for integration into practice-based or hospital based-clinical data management systems.
Konan’s products feature a permission-based remote access tool that allows remote technical support and training.